The spike in deaths – caused by the synthetic opioid Fentanyl – rose from 29 deaths per 100,000 people in 1999 to 14.9. SHARE Twitter Facebook Send to a Friend Leave a Reply Cancel replyYour email address will not be published. Required fields are marked *Comment Name * Email * Website Save my name, email, and website in this browser for the next time I comment. Notify me of follow-up comments by email. Notify me of new posts by email.